Infectious Diseases and Antimicrobial Stewardship in Critical Care Medicine 4E has been fully updated and revised. The clinical diagnostic approach to common infectious disease problems in the CCU is the underlying theme in the book. Emphasized throughout is the importance of formulating an accurate early presumptive clinical syndrome diagnosis which is the basis for selecting optimal initial antimicrobial therapy in the CCU. Without an accurate presumptive clinical diagnosis, effective therapy is unlikely at best. Based on the most probable clinical diagnosis, optimal antibiotic empiric therapy, based on antimicrobial stewardship principles, minimizes resistance and antibiotic complications in the CCU.
SECTION I: CLINICAL DIAGNOSTIC APPROACH IN THE CRITICAL CARE UNIT
1. Diagnostic Reasoning and Clinical Problem Solving
Burke A. Cunha
2. Clinical Approach to Fever in the Critical Care Unit
Burke A. Cunha
3. Physical Exam Clues and Their Mimics in Infectious Diseases in the Critical Care Unit
Yehia Y. Mishriki
4. Ophthalmologic Clues to Infectious Diseases and Their Mimics in the Critical Care Unit
Cheston B. Cunha, Michael J. Wilkinson, and David A. Quillen
5. Radiology of Infectious Diseases and Their Potential Mimics in the Critical Care Unit
Jocelyn A. Luongo, Boris Shapiro, Orlando A. Ortiz, and Douglas S. Katz
6. Non-specific Laboratory Tests in the Critical Care Unit
Charles W. Stratton
7. Infections and Their Mimics in Returning Travelers in the Critical Care Unit
Elise Kochoumian, Jonathon Moore, Bushra Mina, and Kevin Cahill
8. Diagnostic Approach to Rash and Fever in the Critical Care Unit
Lee S. Engel, Charles V. Sanders, and Fred A. Lopez
9. Severe Tick-Borne Infections and Their Mimics in the Critical Care Unit
Praveen Sudhindra and Gary P. Wormser
SECTION II: CLINICAL SYNDROMIC APPROACH IN THE CRITICAL CARE UNIT
10. The Clinical Approach to Sepsis and Its Mimics in the Critical Care Unit
Abdullah Chahin and Steven M. Opal
11. Acute Bacterial Meningitis and Its Mimics in the Critical Care Unit
Burke A. Cunha
12. Encephalitis and Its Mimics in the Critical Care Unit
John J. Halperin
13. Severe Community-Acquired Pneumonia in the Critical Care Unit
Burke A. Cunha
14. Legionnaire’s Disease and Severe Pneumonia Mimics in the Critical Care Unit
Burke A. Cunha
15. Severe Influenza Pneumonia and Its Mimics in the Critical Care Unit
Eleni E. Magira
16. Severe Non-influenza Viral Pneumonia in the Critical Care Unit
David Waldner, Thomas J. Marrie, and Wendy Sligl
17. Nosocomial Pneumonia in the Critical Care Unit
Burke A. Cunha
18. Central Venous Catheter Infection in the Critical Care Unit
Emilio Bouza and Almudena Burillo
19. Acute Infective Endocarditis and Its Mimics in the Critical Care Unit
John L. Brusch
20. Diagnostic Approach to Myocarditis in the Critical Care Unit
Shabnam Seydafkan and Jason M. Lazar
21. Intra-Abdominal Surgical Infections and Their Mimics in the Critical Care Unit
Donald E. Fry
22. Clostridium difficile and Its Mimics in the Critical Care Unit
Burke A. Cunha
23. Diagnostic Approach to Fulminant Hepatitis in the Critical Care Unit
Huei-Wen Lim and David Bernstein
24. Diagnostic Approach to Acute Kidney Injury in the Critical Care Unit
Sonali Gupta, Divyansh Bajaj, Sana Idrees, and Joseph Mattana
SECTION III: CLINICAL APPROACH TO INFECTIONS IN COMPROMISED HOSTS IN THE CRITICAL CARE UNIT
25. Overwhelming Post-Splenectomy Infections in the Critical Care Unit
Larry I. Lutwick and Jana Preis
26. Infections in Cirrhosis in the Critical Care Unit
John M. Horne and Laurel C. Preheim
27. Febrile Neutropenia in the Critical Care Unit
Perrine Parize, Anne Pouvaret, Paul-Louis Woerther, Frédéric Pène, and Olivier Lortholary
28. Infections Related to Steroids and Immunosuppressive Agents in the Critical Care Unit
Gülden Yilmaz and Müge Ayhan
29. Infections in Solid Organ Transplant Recipients Admitted to the Critical Care Unit
Almudena Burillo, Patricia Muñoz, and Emilio Bouza
30. Care of Critically Ill Patients with HIV
Joseph Metmowlee Garland, Andrew Levinson, and Edward Wing
SECTION IV: ANTIMICROBIAL THERAPY AND ANTIBIOTIC STEWARDSHIP IN THE CRITICAL CARE UNIT
31. Principles of Antibiotic Stewardship in the Critical Care Unit
Cheston B. Cunha
32. Colonization, Infection, and Resistance in the Critical Care Unit
Edward J. Septimus
33. Rapid Infectious Diseases Diagnostics in the Critical Care Unit
Bronwen Garner and Kimberly Hanson
34. Antibiotic Therapy of Multidrug Resistant Organisms in the Critical Care Unit
Burke A. Cunha
35. Antibiotic Therapy in the Penicillin-Allergic Patient in the Critical Care Unit
Burke A. Cunha
36. Adverse Reactions to Antibiotics in the Critical Care Unit
Diane M. Parente, Cheston B. Cunha, and Michael Lorenzo
37. Antibiotic Dosage Adjustment in Renal Insufficiency and Hemodialysis in the Critical Care Unit
Damary C. Torres, Kristina Bruno, and Danielle Maffei
38. Antibiotic Failure: Apparent or Actual in the Critical Care Unit
Burke A. Cunha